譜析（上海）生物科技有限公司提供——Hemoglobin Variants and ?-Thalassemia Screening in Whole Blood 質(zhì)譜診斷方案
 
一、說明
Defects in genes, which are responsible for the synthesis of the hemoglobin molecule, result in a group of hereditary diseases termed as "hemoglobinopathies". Depending on the molecular defect, hemoglobinopathies may be classified in "structural hemoglobin variants" and in "thalassemias". This test kit allows a reliable separation and identification of the common and clinically significant hemoglobin variants. For B-thalassemia screening the kit ensures an exact quantification of HbF and HbA2. A ready for use test solution (containing: HbA1c, HbF, HbAO, HbE, HbA2, HbD, Hbs, HbC), a hemolysate calibrator (containing: HbF, HbA2) as well as hemolysate controls in two levels of concentration are available for quality assurance.
 
二、產(chǎn)品優(yōu)勢
（1）可靠地分離和定量HbA2和HbF
（2）Hbs、HbC、HbE和HbD的安全識別
（3）可提供測試溶液，校準器和控制材料
 
三、測試數(shù)據(jù)
Intraassay precision:      1.0 - 3.3 % (HbF)
0.6 - 3.6 % (HbA2)
Interassay precision:       2.1 - 2.8% (HbF)     
0.7 - 2.4 (HbA2)
Dependence on total hemoglobin:
The HbF and HbA2 values are independent on the amount of total hemoglobin in a range from 6-24 g/dl total hemoglobin. 
 
四、高效液相色譜參數(shù)
Pump:                       binary gradient pump
Flow rate:                  1.2 ml/min
Injection volume:           20 μl
Injection interval:         8 min
UV/VIS-Detector:            415 nm
HPLC-Thermostat:            23 °C
 
五、樣品制備
 
 
 
六、訂購信息
 

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