譜析（上海）生物科技有限公司優(yōu)勢供應(yīng)：S.aureus Gyrase Cleavage Assay Kits(金黃色葡萄球菌卵裂試劑盒)
2019/10/12 11:48:55
一些藥物中斷了旋轉(zhuǎn)酶反應(yīng)的DNA斷裂-重組步驟。這導(dǎo)致細(xì)胞死亡，這是喹諾酮類藥物，如納立二酸和環(huán)丙沙星作用背后的機制。卵裂分析在確定潛在藥物是否通過這一機制起作用時特別有用。這些試劑盒是專門為裂解反應(yīng)設(shè)計的。除了金黃色葡萄球菌旋轉(zhuǎn)酶和線性化的pBR322標(biāo)記物外，它們還含有超螺旋的pBR322 DNA底物和DNA裂解反應(yīng)所需的分析和稀釋緩沖液。解理特定的酶可單獨要求。
Some drugs interrupt the DNA breakage-reunion step of the gyrase reaction. This leads to cell death and it is the mechanism behind the action of the quinolones such as nalidixic acid and ciprofloxacin. Cleavage assays are particularly useful in determining if a potential drug acts by this mechanism.
These kits are designed specifically for cleavage reactions. They contain the supercoiled pBR322 DNA substrate and the Assay and Dilution buffers required for DNA cleavage reactions in addition to the S. aureus gyrase and linearised pBR322 marker.
Cleavage specific enzyme available separately on request.
優(yōu)勢供應(yīng)產(chǎn)品：
譜析（上海）生物科技有限公司是一家致力于為實驗室分析領(lǐng)域
更多產(chǎn)品請咨詢上海熹垣生物。
Some drugs interrupt the DNA breakage-reunion step of the gyrase reaction. This leads to cell death and it is the mechanism behind the action of the quinolones such as nalidixic acid and ciprofloxacin. Cleavage assays are particularly useful in determining if a potential drug acts by this mechanism.
These kits are designed specifically for cleavage reactions. They contain the supercoiled pBR322 DNA substrate and the Assay and Dilution buffers required for DNA cleavage reactions in addition to the S. aureus gyrase and linearised pBR322 marker.
Cleavage specific enzyme available separately on request.
優(yōu)勢供應(yīng)產(chǎn)品：
| Cat No. | Product | Product description |
| SAGC001 | S.aureus Gyrase Cleavage Assay Kit 1 |
100 U of S. aureus gyrase and 50 ug of supercoiled DNA |
| SAGC002 | S.aureus Gyrase Cleavage Assay Kit 2 |
500 U of S. aureus gyrase and 50 ug of supercoiled DNA |
